Copper-Catalyzed Annulation of Isothiocyanates with Diaryliodonium Salts:Arylation-Cyclization Appro

来源 :中国化学会全国第十二届有机合成化学学术研讨会 | 被引量 : 0次 | 上传用户：victor530505911

【摘要】

：

【作者】

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Wang Yuan-Chao Guo Wei-Si Wen Li-Rong

【机构】

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College of Chemistry and Molecular Engineering,Qingdao University of Science and Technology,Qingdao,

【出处】

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中国化学会全国第十二届有机合成化学学术研讨会

【发表日期】

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2015年7期

【关键词】

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quinolines isothiocyanate diaryliodonium salts

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　　Quinolines are privileged scaffolds in various bioactive natural products and pharmaceuticals.1 Therefore,many methods for the synthesis of quinolines have been developed including Combes quinoline synthesis,Friedlander synthesis,Skraup synthesis and so on.Based on our previous studies on the diaryliodonium salts,we herein reported a novel copper-catalyze tandem arylation-cyclization process for the preparation of quinolines from readily available isothiocyanates with diaryliodonium salts.

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Copper-Catalyzed Annulation of Isothiocyanates with Diaryliodonium Salts:Arylation-Cyclization Appro

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