【摘 要】
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Allenes are a class of unique compounds with two π-orbitals perpendicular to each other.For various substituted allenes,the respective C=C double bonds represent different reactivities.This would make
【机 构】
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School of Chemistry and Material Science, Liaoning Shihua University, Dandong Road 1, Fushun 113001
【出 处】
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中国化学会第十三届全国有机合成化学学术研讨会
论文部分内容阅读
Allenes are a class of unique compounds with two π-orbitals perpendicular to each other.For various substituted allenes,the respective C=C double bonds represent different reactivities.This would make the controlling of chemo-,regio-,and stereoselectivity possible.Recently,the highly stereoselective bromination of 1,2-allenylic diphenyl phosphine oxides has been realized in our group by using copper (Ⅱ) bromide both as the reacting partner and the catalyst,providing an efficient method for synthesizing β-bromo-γ-hydroxyprop-α-alkenyl diphenyl phosphine oxides (3) or β,γ-dibromo-α-alkenyl diphenyl phosphine oxides (2).The reaction conditions are exceptionally mild,and a wide range of functional groups are well tolerated.
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