【摘 要】
:
A case of intracerebral schwannoma is presented.A 19-year-old right-handed boy presented to our department after an epileptic seizure 5 days before.He was investigated by Computed tomography and Magne
【机 构】
:
Department of Neurosurgery,the First Affiliated Hospital of Nanchang University,No.17 Yongwaizhengji
【出 处】
:
中华中青年神经外科交流协会第二届学术大会
论文部分内容阅读
A case of intracerebral schwannoma is presented.A 19-year-old right-handed boy presented to our department after an epileptic seizure 5 days before.He was investigated by Computed tomography and Magnetic resonance imaging which showed a 3.5×2.5cm, intraaxial, contrast-enhanced cortical lesion in the right frontal lobe, with peritumoral edema and a dural-based attachment.The initial diagnosis was meningioma.Histopathological examination revealed schwannoma.At surgery, a rim of intact pia was identified between the duraand the tumor, the tumor was removed completedly.Histologically, the tumor demonstrated classic biphasicAntoni type A and Antoni type B patterns, and small aggregates of Schwann cells spread extensively into the surrounding brain tissue adjacent to the tumor nodule.Immunohistochemically, the neoplastic cells were positive for S-100 protein, CD56 and vimentin, while none was positive for C D34, PAS ,CEAor epithelial membrane antigen (EMA).The patients postoperative course was unremarkable and he remains seizure-free at 12months after surgery.Intracerebral schwannoma is a rare cortical lesion which is usually misdiagnosed as meningioma or glial tumor preoperatively, the related literature was reviewed and the imaging findings of intraparenchymal schwannomas were discussed.
其他文献
目的:由于胶质母细胞瘤的侵袭特性以及肿瘤边界不清,肿瘤完全切除是很难达到的.术中核磁共振由于价格等因素还不能普及.5-ALA等肿瘤荧光技术特异性一般,分辨率较低,使用受到限制.我们希望发明一种高分辨率的高度特异性的术中实时探测肿瘤的技术来提高胶质母细胞瘤的切除比率.方法:我们采用绿色荧光修饰的塞内卡病毒(SVV-001-GFP)作为肿瘤细胞的荧光标记物.在术前48小时通过尾静脉注射SVV-GFP病
目的:探讨蝶骨嵴内侧巨大脑膜瘤的显微手术技巧与围手术期并发脑梗塞的相关问题。方法:回顾性总结68例巨大型蝶骨嵴内侧脑膜瘤的临床资料,重点分析手术技巧与围手术期脑梗塞发生的相关病理关系。结果:接受手术治疗的68例巨大型蝶骨嵴内侧脑膜瘤中,显微手术全切62例,次全切6例,其中2例在术后围手术期内出现脑梗塞(大脑中动脉脑梗塞1例,基底节脑梗塞1例),症状进行性加重,出现颅内压增高,后因脑疝形成致死。术中
临床上需要于术前、术后准确评估听神经瘤患者面神经损伤程度,以此判断听神经瘤患者的病情、预后以及手术疗效。本文的目的是介绍面神经功能评价体系的发展历史,参照House-Brackmann分级法、线性测量指数(LMI)、面神经功能指数(FNFI)、诺丁汉分级系统(Nottingham system)、多伦多分级法(TFGS)等评价体系,寻找一些针对周围性面瘫进行神经功能评价的指标,以便有针对性的评价听
目的:探讨miR-16在人脑胶质瘤表达以及与胶质瘤细胞株SHG4、U87和U373侵袭和生长的相关性,为miR-16作为治疗人脑胶质瘤的靶点奠定基础.方法:利用定量PCR检测miR-16、NF-κ B1在非瘤脑组织和不同级别人脑胶质瘤中的表达.采用Lipofectamine2000脂质体法将化学合成的mir-16寡核苷酸随机序列分别转染上述细胞系.利用划痕试验Transwell小室模型观察miR-
目的: 探讨NFKBIA蛋白表达与NFKBIA变异、mRNA表达、拷贝数及预后的关系。方法:通过分析24例胶质母细胞瘤及8个非瘤脑组织中NFKBIA变异、蛋白表达及mRNA表达水平、拷贝数变异情况,比较分子结果与24例胶质母细胞瘤的预后关系。结果:胶质母细胞瘤中NFKIBA仅有一个单核苷酸多态性,rs1957106,其与NFKBIA低蛋白表达、低拷贝数密切相关,可能与相对短生存期密切相关。结论:N
目的:利用磁共振成像(magnetic resonance imaging,MRI)观察原发性三叉神经痛患者的三叉神经脑池段与周围血管间的空间关系,评估术前核磁对血管接触诊断的有效性.方法:回顾性分析2011年1月至2012年11月89例三叉神经痛微血管减压术患者的术前核磁影像和手术录像.MRI成像使用1.5T磁共振采集时间飞跃(TOF)序列和稳态构成干扰(CISS)序列,研究患侧和健侧三叉神经脑
目的 探讨三叉/舌咽神经交界区疼痛的手术治疗方法.方法 3例三叉/舌咽神经交界区疼痛患者,2例经单纯舌咽神经痛手术治疗无效,经重新探讨机制,3例皆行三叉/舌咽神经显微血管减压术+迷走神经耳咽支扩大切断术治疗.结果 3例患者术后疼痛消失,其中2例随访1.5年,1例随访1年,都无复发.结论 对于三叉/舌咽神经交界区疼痛,宜采取三叉/舌咽神经显微减压术和舌咽神经/迷走神经耳咽支切断术的复合术式,以保障手