Hard and soft structural composites found in biology provide inspiration for the design of advanced synthetic materials.Many examples of bio-inspired hard materials can be found in the literature; far less attention has been devoted to soft systems.Here we introduce deterministic routes to low-modulus thin film materials with stress/strain responses that can be tailored precisely to match the non-linear properties of biological tissues,with application opportunities that range from stretchable biomedical electronics to constructs for tissue engineering [1].