Surface Modification of Doxorubicin-loaded Poly(lactic acid) Nanoparticles with Mn(Ⅲ) chelate for Po

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  Recently, for theranostic use, nanoplafforms for integrating the functions of magnetic resonance imaging (MRI) and drug delivery have been fabricated for the treatment of cancer to enable improved diagnosis and real-time monitoring, resulting in significantly improved efficacy and therapeutic outcomes.Actually, for realizing the function of MRI, there are several virtues of low molecular weighted paramagnetic metal complexes relative to Fe3O4 NPs, such as high contrast ability and easily urinary excretion.
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