The Treatment of Endometriosis Using Oral Contraceptives Associated with Natural NF-Kappa.b and Arom

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  When used in extended regimens, oral contraceptives are effective in reducing pain in patients with endometriosis.This effect is due to the progestin component of the pill and is mediated through several mechanisms involving not only the blockade of NF-Kappa.b activation but also the inhibition of aromatase p450 and Cox-2 in both endometriosis lesions and in the eutopic endometrium.
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