论文部分内容阅读
Design, Synthesis and Evaluation of Tacrine-Cinnamic Acid hybrids as multi-target Acetyl-and Butyroc
【机 构】
:
Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing,210009, China
【出 处】
:
2016年长三角药物化学研讨会
【发表日期】
:
2016年11期
其他文献
Design, synthesis and preliminary biological evaluation of novel inhibitors of smoothened (SMO) rece
会议
An affinity-based fluorescence polarization assay for high-throughput screening of prolyl hydroxylas
Prolyl hydroxylase domain 2 (PHD2) enzyme,a FeⅡ and 2-oxoglutarate (2-OG)dependent oxygenase,which mediate key physiological responses to hypoxia by modulating the levels of hypoxia inducible factor 1
Identification of novel JMJD2A inhibitor scaffold using shape and electrostatic similarity search co
会议
Optimization and biological evaluation of celastrol derivatives as Hsp90-Cdc37 interaction disruptor
会议
会议
Systhesis and evaluation of N-(benzofuran-5-yl) aromaticsulfonamide derivatives as novel HIF-1 inhib
Hypoxia-inducible factor-1 (HIF-1) as a key mediator in tumor metastasis,angiogenesis,and poor patient prognosis has been recognized as an important cancer drug target.1-4 So far,several HIF-1 inhibit
会议
Structure-based Design and Synthesis of Small Molecular Inhibitors Disturbing the Interaction of MLL
会议
Design, Synthesis, and Initial Evaluation of Affinity-Based SmallMolecule Probes for Fluorescent Vis
Kelch-like ECH-associated protein-1 (Keap 1) is a pluripotent protein,which plays an important role in stress responses,especially in oxidative stress.Firstly,Keapl is an important adaptor compo-nent
会议