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Objective Lung cancer continues to be the most frequent cancer,non-small-cell lung cancer(NSCLC)accounts for approximately 80%of all lung cancers.The RAD51 protein is the key protein for homologous recombination,an evolutionarily conserved mechanism for DNA damage repair and the generation of genetic diversity.This study aims to investigate the effects of RAD51AP1 on epithelial-mesenchymal transition(EMT)and metastasis in non-small cell lung cancer(NSCLC).