Accumulating evidence has proved that mitochondrial metabolism and functions are closely linked with tumor initiation and progression.Mitophagy,a selective
Cytochrome P450(P450)enzymes are the major catalysts involved in the metabolism of drugs,steroids,chemical carcinogens,and fat-soluble vitamins.Collectively
Protein function originates from a cooperation of structural rigidity,dynamics at different timescales and allostery.However,how these three pillars of prot