【摘 要】
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This study identified differences in plasma metabolites among three groups of dairy cows:type Ⅰ ketotic (K1),type Ⅱ ketotic (K2), and healthy control cows (C).Plasma metabolomic profiles were analyzed
【机 构】
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College of Animal Science and Veterinary Medicine ,Heilongjiang Bayi Agricultural University ,Daqing
【出 处】
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中国畜牧兽医学会家畜内科学会2014年学术研讨会
论文部分内容阅读
This study identified differences in plasma metabolites among three groups of dairy cows:type Ⅰ ketotic (K1),type Ⅱ ketotic (K2), and healthy control cows (C).Plasma metabolomic profiles were analyzed by 1H-nuclear magnetic resonance technology (1H NMR).The data were processed by principal component analysis (PCA) and orthogonal partial least-squares discriminant analysis (OPLS-DA).The results revealed that OPLS-DA was more effective at distinguishing amongst the three groups.Additionally, there were seven different metabolites between K2 and C, 19 different metabolites between K1 and C, and 24 different metabolites between K1 and K2.Therefore, the combination of 1H-NMR and multivariate statistical analyses can effectively distinguish the differential metabolites among the K1, K2, and C groups, thereby providing important information on the pathogenesis, early diagnosis, and prevention of type Ⅰ and type Ⅱ ketosis in dairy cows.
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