BTG4 is a key regulator for maternal mRNA clearance during mouse early Embryogenesis

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户:shuzhong12miyan
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  Maternal mRNAs degradation is a crucial process in the early embryonic development.However,the mechanism and regulators governing maternal mRNAs clearance remains unclear in mammals.The CCR4-NOT complex plays predominant roles in mRNAs deadenylation that is the first and often rate-limiting step accounting for mRNA turnover.
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