A surface-imprinted chiral stationary phase for the enantiomeric resolution of the antidepressant drug citalopram is presented in this work.N,N’- diethylaminodithiocarbamoylpropyl-(trimethoxy)silane has been used as silane iniferter for the surface functionalisation of the solid silica support.A MIP thin film,in the nm scale,was then grafted on the silanised silica using itaconic acid as the functional monomer,ethylene glycol dimethacrylate as the cross-linker in the presence of the template,S-citalopram (SCIT).