【摘 要】
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Background Several headache models have been established to date based on dural stimulation,but most of these are built based on single stimulation,while migraineur experiences repeated dural nocicept
【机 构】
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Department of Neurology,West China Hospital,Chengdu,Sichuan,China
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Background Several headache models have been established to date based on dural stimulation,but most of these are built based on single stimulation,while migraineur experiences repeated dural nociceptive activation,In addition,clinical trials in patients have been failed to confirm the efficacy of the anti-migraine drugs which was once useful in traditional animal models.Considering the need for a new model,we establish a recurrent headache model in conscious rhesus monkey by episodic dural stimulation.
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