The chiral liquid crystal (CLC) phase of pristine graphene oxide have been disclosed recently, opening an avenue to high performance neat graphene fibers.Here, we report for the first time LC of polymer-grafted GO and its macroscopic assembled nacre-mimetic composite.The PAN-grafted GO (GO-g-PAN) sheets, prepared by a simple in situ free radical polymerization process, were well dispersed in polar organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO),forming nematic and lamellar LCs upon increasing concentration.Strong signal was found in the circular dichroism spectra of the LCs, indicating the formation of helical stru4ctures for the GO-g-PAN LCs.