【摘 要】
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In recent years, genome-wide association studies on systemic lupus erythematosus (SLE) have significantly improved our understanding of the genetic architecture of this prototypic autoimmune disease.H
【机 构】
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Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
【出 处】
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中国免疫学会第九届全国免疫学学术大会
论文部分内容阅读
In recent years, genome-wide association studies on systemic lupus erythematosus (SLE) have significantly improved our understanding of the genetic architecture of this prototypic autoimmune disease.However, there is still a long way to go before we can fully understand the genetics of this very heterogeneous disease, as the susceptibility genes discovered only explain a small fraction of disease heritability.Here we summarize the recent advances in SLE genetics and discuss the future directions toward a better understanding of the genetic architecture of SLE.
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