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Sodium carbonate (Na2CO3) presents a huge challenge to plants by the combined damaging effects of Na+, high pH and CO32-.Little is known about the cellular responses to Na2CO3 stress.In this study, the transcriptome of maize (Zea mays L.cv.B73) roots exposed to Na2CO3 stress for five hours were compared with those of NaC1 and NaOH stresses.