• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. Anti-apoptotic and neuroprotective effects of oxysophoridine on cerebral ischemia both in vivo and i

Anti-apoptotic and neuroprotective effects of oxysophoridine on cerebral ischemia both in vivo and i

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：cwg8872757
【摘 要】
：
Aim: In this study we investigated the neuroprotective effect of oxysophoridine (OSR) on ischemia and ischemia-like insults.Methods: Protection by oxysophoridine (OSR) was studied in vivo level using
【作 者】
：
Ru ZHOU Rui CHEN Yu-xiang LI Ning-tian MA Qing-luan ZHU Yin-ju HAO Lin MA Tao SUN Jian-qiang YU 
【机 构】
：
Department of Pharmacology, Ningxia Medical University, Yinchuan 750004, China; Ningxia collaborativ
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
oxysophoridine (OSR) Cerebral ischemia middle cerebral artery occlusion (MCAO) o 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Aim: In this study we investigated the neuroprotective effect of oxysophoridine (OSR) on ischemia and ischemia-like insults.Methods: Protection by oxysophoridine (OSR) was studied in vivo level using a model of middle cerebral artery occlusion (MCAO) in mice and in vitro level using primary rat hippocampal neuronal cultures exposed to oxygen-glucose deprivation (OGD), a model of ischemia-like injury.
其他文献
Translational regulation of RPA2 via internal ribosomal entry site and by elF3a
Aim: RPA2 is a subunit of a trimeric RPA complex important for DNA repair and replication.Although it is known that RPA activity is regulated by posttranslational modification, whether RPA expression
会议
eIF3areplication protein A (RPA)cellular internal ribosome entry sites (IRES)
P-glycoprotein mediated efflux of aconitine in vitro, in situ and in vitro
Aim: Aconitine (AC) is a toxic alkaloid from some Chinese medicinal herbals with origin of genus Aconitum, which have been widely used for analgesic, cardiotonic and anti-rheumatism treatment.To asses
会议
aconitineP-glycoproteinpermeabilityoralabsorption
Traditional Chinese medicine with reinforcing kidney activity ameliorate experimental autoimmune enc
Aim: The present study was designed to determine whether traditional Chinese medicine with reinforcing kidney activity such as cornel iridoid glycoside (CIG) and epimedium flavonoids (EF) had effect o
会议
experimental autoimmune encephalomyelitiscornel iridoid glycosideepimedium fla
Berberine improves glucose consumption in cardiomyocytes via activation of 5'-adenosine monopho
Aim: Insulin resistance plays an important role in the pathogenesis of diabetic cardiomyopathy.Berberine (BER) is a plant alkaloid which promotes hypoglycemia via increasing insulin sensitivity in per
会议
berberineglucose consumptioncardiomyocyteAMPK
GanDanLiangYiTang exerts sedative and hypnotic activities by elevating amino acids neurotranmitters
Aim: To study the sedative and hypnotic effects of GanDanLiangYiTang (GDLYT) and the potential mechanism in mice.Methods: The KM mice were divided into seven groups: the control group, the diazepam gr
会议
GanDanLiangYiTangmicesedative hypnoticcentral neurotrasmitter
Effect of Mongolian medicine Garidi-13 on neurological score, pathological changes, serum levels of
Aim: To study the effect of Garidi-13 on neurological score, pathological changes,serum levels of NSE, TNF-α, IL-1β, IL-6, IL-8 at different phases during cerebral ischemia in rats and investigate pro
会议
Mongolia drug Garid-13cerebral ischemiaTNF-αIL-1βIL-6IL-8NSE
Antidepressant, anxiolytic and anti-PTSD effects of YL-IPA08, a potent ligand for the translocator p
Aim: The translacator protein (18 kDa) (TSPO), previously called peripheral bernzodiazepine receptor, is the key element of the mitochondrial import machinery supplying the substrate cholesterol to th
会议
the translocator protein 18 kDaYL-IPA08anxiolyticantidepressantneurosteroids
Protocatechuic acid protects primary astrocytes against MPP+-induced oxidative stress and apoptosis
Aim: Protocatechuic acid (PCA), a phenolic compound, has been reported to exert neuroprotective effects, but its effect on astrocytes has not been studied.The aim of this paper is to investigate wheth
会议
protocatechuic acidoxidative stressapoptosismitochondrial membrane potential
A transmembrane accessory subunit that modulates kainate-type glutamate receptors
Glutamate receptors play major roles in excitatory transmission in the vertebrate brain.Among ionotropic glutamate receptors (AMPA, kainate, NMDA), AMPA receptors mediate fast synaptic transmission an
会议
Effects of HSW on mice model of Parkinson's disease induced by MPTP
Aim: To observe the effects of HSW on behavior and content of dopamine (DA), DOPAC and HVA in the striatum of mice treated with 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP).Methods: C57BL mi
会议
PDCs7BL micebehavior testdopamine