Hyaluronic Acid (HA)-Coated PEI-PLGA Nanoparticles for Co-delivery of miR-542-3p and Doxorubicin In

来源 :纳米药物及纳米生物技术国际学术大会暨中国药学会纳米药物专业委员会成立大会 | 被引量 : 0次 | 上传用户：energyjx

【摘要】

：

【作者】

：

Shengpeng Wang Jinming Zhang Yitao Wang Meiwan Chen

【机构】

：

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences,

【出处】

：

纳米药物及纳米生物技术国际学术大会暨中国药学会纳米药物专业委员会成立大会

【发表日期】

：

2015年11期

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MicroRNAs (miRNAs) play critical roles in modulating the oncogenic pathways that are involved in the resistance to cancer treatments.Several studies have reported that miR-542-3p serves as a potent tumor suppressive molecule in many types of cancers via targeting the tumor suppressor gene p53 and the apoptotic inhibitor survivin.

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