Since nanoparticles have the size comparable to the innercellular organs,they have potentially the nature to induce the simultaneous cell reaction,which makes nanoparticles characterized as biointeractive.Through this biological process,materials show the functions in nano different from in macro such as mesothelioma in asbestos and bone substitutable apatite[1].Therefore to understand the cell function in response to nanoparticles,it is necessary to observe the dynamical behavior of living cells in action.