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  5. Nanodiamond loading insoluble sorafenib enhances oral delivery and inhibited tumor metastasis of gas

Nanodiamond loading insoluble sorafenib enhances oral delivery and inhibited tumor metastasis of gas

来源 :International Conference on Nanoscience & Technology,China 2 | 被引量 : 0次 | 上传用户：houjinlei11
【摘 要】
：
Tumor metastasis is one of the greatest hurdles for cancer treatment, which accounts for 90% of cancer-associated mortality.Nanodiamond (ND) presents many requisite properties of drug delivery system
【作 者】
：
Zhiwen Zhang Baohua Niu Yixin Wang Xiaoyue Bao Yaping Li 
【机 构】
：
Center of Pharmaceutics,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 20
【出 处】
：
International Conference on Nanoscience & Technology,China 2
【发表日期】
：
2013年3期
【关键词】
：
Nanodiamond Sorafenib Oral delivery Tumor metastasis 
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　　Tumor metastasis is one of the greatest hurdles for cancer treatment, which accounts for 90% of cancer-associated mortality.Nanodiamond (ND) presents many requisite properties of drug delivery system and is promising to deliver a wide range of therapeutics.Herein, ND loading insoluble sorafenib (SND) was used to enhance the oral delivery, and inhibit the liver and kidney metastasis of gastric cancer.
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