Synthetic Investigation toward Antitumoral Lignan Glycosides

来源 :第二届糖合成化学青年学术研讨会 | 被引量 : 0次 | 上传用户：thd111

【摘要】

：

Lignan glycosides are ideal resources for antitumoral agents development.As semisynthetic lignan glycosides etoposide and teniposide have been widely used as an

【作者】

：

Hui Liu Lei Liu Jun-Hao Wan Jian-Song Sun

【机构】

：

NationalResearchCenterforCarbohydrateSynthesis,JiangxiNormaolUniversity,Nanchang330022

【出处】

：

第二届糖合成化学青年学术研讨会

【发表日期】

：

2017年5期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Lignan glycosides are ideal resources for antitumoral agents development.As semisynthetic lignan glycosides etoposide and teniposide have been widely used as antitumoral agents in clinical,[1] while another semisynthetic lignan glycoside,NK-611,is now in phse Ⅱ clinical trial.

其他文献

3-氨基脱氧糖的多样性合成及其糖苷键的构建

会议

氨基脱氧多样性合成糖苷键

Design and Synthesis of tetra/pentacyclic iminosugar derivatives fused thiazinan-4-one as potential

　　Iminosugars or azasugars,which exhibit effective inhibition against carbohydrate-processing enzymes,have attracted great interest for their potential clinic

会议

Resolving the α-Glycosidic Linkage of Arginine-Rhamnosylated Translation Elongation Factor P(EF-P)Tr

会议

有机膦氯化金催化剂的高效制备及其在糖类药物金诺芬合成中的应用

金催化剂被广泛地应用于有机合成中,如π-体系的亲核加成、氢化、氧化、碳氢活化以及糖苷化反应.同时,金催化剂与配体形成的金配合物通常具有优异的抗炎、抗癌和抗寄生虫活性

会议

Studies toward the Chemical Synthesis of Homogeneously Glycosylated Interferon Gamma

Interferon gamma(IFN-γ) is an important N-glycosylated protein produced primarily by T-lymphocytes and natural killer cells.1 As a cytokine that is crucial for

会议

GalactoseLactose-based Glyco-nanovesicles for Targeted Drug Delivery

The targeted drug delivery systems based on glyco-nanovesicles(GNVs) have been developed,where the GNVs were obtained via either the self-assembly of the amphip

会议

苝酰亚胺-糖类化合物的合成及功能研究

糖与蛋白间高度专一性识别和粘附作用在细胞的生长、分裂、免疫调节和癌细胞转移等识别过程中起着重要作用.然而由于单糖分子与蛋白间的作用较弱,生物体中通过所谓的"多价效

会议

Efficient and Practical Synthesis of Fondaparinux

会议

一种奇特结构的根瘤菌O-抗原寡糖的合成

会议

结构根瘤菌抗原寡糖

Chemically-Defined Natural N-Glycan Scaffold Efficiently Delivers Toxins to B-Lymphoma Cells

CD22 is a sialic acid-binding immunoglobulin-like lectin(Siglec) that is highly expressed on B-cell lymphomas,and is a validated target for antibody and nanopar

会议

Synthetic Investigation toward Antitumoral Lignan Glycosides

与本文相关的学术论文