AEI analysis is a powerful tool of discovering cis-acting regulatory variants in candidate genes. Ourstudy of TPH2 provides a general model for discovering and
Functional modulation of Kv4 channels by auxiliary KChIPs is of an extreme complexit-y. Recentco-crystal structure of Kv4 N-terminus/KChIP complex reveals a uni
The pathogenesis of Down syndrome remains unknown. Some genes triplicated in Down sy-ndromewere proposed to contribute to the pathogenesis of DS and also the de