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  5. The effect of sevoflurane on dentritic spine and spacial memory is meditated by α7nAChR-NMDAR in neo

The effect of sevoflurane on dentritic spine and spacial memory is meditated by α7nAChR-NMDAR in neo

来源 :中华医学会第22次全国麻醉学术年会 | 被引量 : 0次 | 上传用户：huei59
【摘 要】
：
Sevoflurane, which is the most commonly used volatile anesthetic in infants, has been reported to cause long-term memory impairment1 in neonatal rats.However, the mechanism is unclear.α7 nicotinic ace
【作 者】
：
X.Tang Y.Li C.Wang M.Yang M.Wang H.Wang GL.Wang 
【机 构】
：
Department of Anesthesiology,General Hospital of Tianjin Medical University, Tianjin, China
【出 处】
：
中华医学会第22次全国麻醉学术年会
【发表日期】
：
2014年11期
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Sevoflurane, which is the most commonly used volatile anesthetic in infants, has been reported to cause long-term memory impairment1 in neonatal rats.However, the mechanism is unclear.α7 nicotinic acetylcholine receptor (α7nAChR) is one of the targets of volatile anesthetics2,and N-Methyl-D-Aspartate (NMDAR) plays an important role in LTP.
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