Id2调控结直肠癌细胞HCT116生长和侵袭转移的机制研究

来源 :2019中国肿瘤学大会 | 被引量 : 0次 | 上传用户：novi005

【摘要】

：

目的探讨Id2对人结直肠癌细胞生长和侵袭转移的影响及作用机制。方法 qRT-PCR 和Western Blot 检测六株人结直肠癌细胞中Id2 mRNA 和蛋白的表达。选取高表达Id2 的肠癌细胞株，感染慢病毒后用puromycin 筛选，构建稳定敲减Id2 的肠癌细胞株。

【作者】

：

刘枋于悦黄传钟陈慧菁王玲张万平叶韵斌

【机构】

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福建省肿瘤医院

【出处】

：

2019中国肿瘤学大会

【发表日期】

：

2019年7期

【关键词】

：

Id2可能通过PI3K/AKT信号通路改变细胞周期蛋白 EMT相关蛋白和MMPs/TIMPs的表达影响结直肠癌细胞的生长和侵袭转移

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Id2调控结直肠癌细胞HCT116生长和侵袭转移的机制研究

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