Deletion of Angiotensin-Converting Enzyme 2 exacerbates kidney inflammation and injury in the apolip

来源 :Ready for 2018- the 4th China International Forum on Hyperte | 被引量 : 0次 | 上传用户：panshuangchun

【摘要】

：

　　Background:Angiotensin-converting enzyme 2 (ACE2) is known as a negative regulator of the RAS, but its role in atheroscierotic renal injury are poorly under

【作者】

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ZhenzhouZhang;LaijiangChen;YingleXu;RanXu;QingChang;PingjinGao;DingliangZhu;JiguangWang;JiuchangZhong;

【机构】

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Shanghai Institute of Hypertension & State Key Laboratory of Medical Genomics,Ruijin Hospital Affili

【出处】

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Ready for 2018- the 4th China International Forum on Hyperte

【发表日期】

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2015年期

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　　Background:Angiotensin-converting enzyme 2 (ACE2) is known as a negative regulator of the RAS, but its role in atheroscierotic renal injury are poorly understood.We hypothesized that ACE2 would exert beneficial effects on renal injury in apolipoprotein E (ApoE)-knockout (KO) mice.

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Deletion of Angiotensin-Converting Enzyme 2 exacerbates kidney inflammation and injury in the apolip

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