生理剂量的双酚A对雄性成年大鼠及其子代空间记忆的影响

来源 :中华医学会第十一次全国精神医学学术会议暨第三届亚洲神经精神药理学术会议 | 被引量 : 0次 | 上传用户：lb878719

【摘要】

：

目的双酚A (BPA)是一种常见的环境内分泌干扰物,超过90％美国人的尿液中可以检测到BPA.研究证实:母亲暴露于BPA可以引起神经系统和行为的永久性改变.但是关于父亲暴露对子代的影响还未见报道.因此,本研究首次探讨了生理剂量BPA对父代及其子代大鼠空间记忆的影响.方法 22只雄性成年大鼠(F0)随机接受BPA(50 μg/kg/d)或对照食物10周后和雌鼠交配.随后父代和成年子代(F1)行水迷

【作者】

：

胡晓华范瑛吴辉华刘燕林王宗琴谢琴包玲高作惠刘恋冯映映江云

【机构】

：

华中科技大学同济医学院附属武汉市精神卫生中心武汉市精神卫生中心

【出处】

：

中华医学会第十一次全国精神医学学术会议暨第三届亚洲神经精神药理学术会议

【发表日期】

：

2013年12期

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生理剂量的双酚A对雄性成年大鼠及其子代空间记忆的影响

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