The Chiral and Bioactive Application Study of Rosin Acid

来源 :中国化学会全国第十二届有机合成化学学术研讨会 | 被引量 : 0次 | 上传用户:chenhaun0702
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  Pine resin,a natural resin obtained from coniferous trees,exhibit some preferable biological activities such as anti-inflammatory,antiseptic and antioxidant.Abietic acid,an important bioactive constituent originally obtained from pine resin,which was reported to have many pharmacological and biological functions,including anticancer,anti-allergic,anti-inflammatory,anticonvulsant,antibacterial properties,as well as lowering cholesterol and inhibiting ATPase activities.Herein,we report the design and synthesis of rosin acid derivatives based on its bioactive and chiral characteristics and their application as antitumor agents and enantioselective agents or catalysts.
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