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Objectives:To compare short-term and long-term change of paraspinal muscle and clinical effect between percutaneous and open pedicle screw fixation in the treatment of thoracolumbar fractures.Methods:Thirty-three patients were divided into four groups:short-term percutaneous pedicle screw fixation group,short-term open pedicle screw fixation group,long-term percutaneous pedicle screw fixation group,and long-term open pedicle screw fixation group.Paraspinal muscle were studied by needle electromyography and CT.Cross-sectional area and color grade information of paraspinal muscle were measured using CT image,and compare clinical variable change among four groups.