Objective The leukocyte integrin LFA-1(CD11a/CD18),which belongs to the β 2 integrin family,is an adhesion factor and plays an important role in the leukocyte trafficking and tumor immune cells.It is
Objective Multiple myeloma(MM)is a B-cell malignancy characterized by the proliferation of plasma cells in the bone marrow(BM).Aberrant glycosylation,as a common post-translational modification in mal
Objective Exploiting gut mucosal immunity to design new antitumor vaccination strategy remains unexplored.Tumor cell-derived microparticles(T-MP)are natural biomaterials that are capable of delivering
Objective Despite the unprecedented success of the clinical application of programmed cell death receptor 1(PD-1)blockade antibodies and CAR-T therapy,treated cancer patients,who initially respond and