<正>Thyroid cancer is a common endocrine malignancy that has recently seen a rapidly rising incidence in many countries in the world, including China.Most patients with thyroid cancer have an excellent prognosis,but some seem to be bound to a poor prognosis with increased disease recurrence,treatment refractoriness,and mortality.The sometimes uncertain behaviors of thyroid cancer can be confusing, making clinical judgment and decision making challenging.Consequently,there have been wide controversies and ongoing debates