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  5. Hypoxia pretreatment mesenchymal stem cells inhibit hypoxia induced cardiac fibroblast activation vi

Hypoxia pretreatment mesenchymal stem cells inhibit hypoxia induced cardiac fibroblast activation vi

来源 :第十二届中国介入心脏病学大会(CIT2014) | 被引量 : 0次 | 上传用户：thonary09
【摘 要】
：
Background Activation of cardiac fibroblasts (CFs) and their differentiation into myofibroblasts (MCFs) is a crucial event in the progression of cardiac fibrosis after myocardial infarction that leads
【作 者】
：
Chen Panpan Hu Xinyang Wu Rongrong Jiang Zhi Xu Yinchuan Wang Kan Zhou Yu Wang Jianan 
【机 构】
：
Cardiovascular Key Lab of Zhejiang Province,Department of Cardiology,the Second Affiliated Hospital,
【出 处】
：
第十二届中国介入心脏病学大会(CIT2014)
【发表日期】
：
2014年3期
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Background Activation of cardiac fibroblasts (CFs) and their differentiation into myofibroblasts (MCFs) is a crucial event in the progression of cardiac fibrosis after myocardial infarction that leads to heart failure.Mesenchymal stem ceils (MSCs),especially hypoxia pretreatment MSCsWT (H-MSCsWT),has been shown to attenuate cardiac fibrosis.The aim of this study was to determine underlying mechanism of H-MSCsWT inactivated cardiac fibroblasts.
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