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蛋白质氧化和硝化与糖尿病的发生发展紧密联系。本文采用免疫共沉淀确证了糖尿病大鼠心肌中的α-烯醇酶是一个容易被氧化和硝化损伤的靶目标,并研究了其羰基和3-硝基酪氨酸的生成对蛋白质结构和功能的影响。在注射链脲霉素6星期后,糖尿病大
Protein oxidation and nitration are closely linked with the occurrence and development of diabetes. In this paper, co-immunoprecipitation was used to confirm that α-enolase in myocardium of diabetic rats was a target easily oxidized and nitrified, and the effects of carbonyl and 3-nitrotyrosine on protein structure and function Impact. After 6 weeks of streptozotocin injection, diabetes is large