【摘 要】
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Objective:To identify the gene expression profile of mandibular condylar cartilage during experimentally induced osteoarthritis (OA).Design:We studied the g
【机 构】
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Peking University
【出 处】
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2005 World DNA and Genome Day(2005中国(大连)国际DNA和基因组节大会)
论文部分内容阅读
Objective:To identify the gene expression profile of mandibular condylar cartilage during experimentally induced osteoarthritis (OA).Design:We studied the gene expression levels in temporomandibular joint (TMJ) condylar cartilage during differentstages of experimentally induced OA.The pathological characteristics of normal,early-stage and late-stage osteoarthritic TMJ cartilage were verified by histological techniques.The gene expression profiles in normal and osteoarthritic cartilage were measured by Affymetrix RAE230A microarrays.Some of the gene transcripts were confirmed by quantitative real-time reverse-transcription PCR analysis.
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