Activation of NF-κB and Respiratory Burst following Aspergillus fumigatus Stimulation of Macrophages

来源 :中华医学会呼吸病学年会——2013第十四次全国呼吸病学学术会议 | 被引量 : 0次 | 上传用户:joeyifeng
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Background Dectin-2, a C-type lectin receptor (CLR), plays an essential role in mediating nuclear factor-kappa B (NF-κB) activation and anti-fungal immunity in response to Candida albicans infection.However, the molecular mechanisms and function of Dectin-2 signalling in response to infection by the pathogenic fungus Aspergillus fumigatus has not been characterized.
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