Objective: The present study is aimed to exploring whether the sternocleidomastoid muscle (SCM) flap transposition to eliminate the dead space in level ⅡB could prevent the postoperative infection in patients underwent supraomohyoid neck dissection (SND).Methods: Ninety-five patients with cN0 oral cancer who underwent SND from March 2011 in our department were included.Forty-eight cases underwent SCM transposition to ⅡB level, the other 47 cases did not.The two groups were matched at age, gender, concomitant diseases, and perioperative treatments.All the patients underwent exhaustive hemostasis and careful placement of negative pressure drainage.The postoperative wound healing was observed during 7 days hospital stay.The infection rates of neck wound healing between the two groups were compared using Fishers exact test.