In modern giant buildings,in order to improve energy utilization efficiency cooling systems have developed from conventional chillers alone to smart energy net which includes chillers,ice storage,groundsource heat pump,CCHP and so on.The reasonable distribution of load is the key to guarantee such system in economical operation.This paper focuses on typical multi-type cooling system,presents economic models of different devices and carries out real-time intelligent economic scheduling with the approach of mixed integer programming.This algorithm has been applied in a certain building of Shanghai and results of simulation show that it is able to provide guidance on intelligent economic scheduling for multi-type cooling system.