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  5. The studies of Xuefuzhuyu oral liquid intervention on the SIRT1 signal transduction mechanism in Isc

The studies of Xuefuzhuyu oral liquid intervention on the SIRT1 signal transduction mechanism in Isc

来源 :微循环国际研讨会暨第十三届全国中西医结合微循环学术会议(International Conference for Mic | 被引量 : 0次 | 上传用户：woshiliuning
【摘 要】
：
Objective: To observe the morphological changes of H9c2 rat myocardial model cells under light microscope following intervention with Xuefuzhuyu oral liquid (XFZY), Oxygen-glucose deprivation (OGD) an
【作 者】
：
Kui-Wu Yao Zhang-Jing Liu 
【机 构】
：
Guang'anmen Hospital,China Academy of Chinese Medical Sciences
【出 处】
：
微循环国际研讨会暨第十三届全国中西医结合微循环学术会议(International Conference for Mic
【发表日期】
：
2013年2期
【关键词】
：
H9c2 rat myocardial cells Ischemic heart diseases Removing blood stasis for prom 
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Objective: To observe the morphological changes of H9c2 rat myocardial model cells under light microscope following intervention with Xuefuzhuyu oral liquid (XFZY), Oxygen-glucose deprivation (OGD) and silent information regulator 2-related enzymes 1 (SIRT1), as well as changes of Sirtl pathway related genes (FOXO family, NF-kB, p53 etc) and cell activities, so as to clarify the gene target and corresponding mechanism of XFZY in the treatment of IHD under the TCM theory of eliminating blood stasis and promoting tissue regeneration.
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