In the recent years,the development of novel nanocarriers for biomedical applications,especially for cancer therapy,has strongly attracted the attention of the scientific community.Among them,mesoporo
Repair of cartilage-bone interface tissue remains challenging,because it combines different cell types and gradients of composition and properties.In recent years,the composition,physical and chemical
In the past few years,delivering clinically approved drugs with nanoscale vehicles (10-200 nm)for enhanced cancer therapy has attracted extensive attention,as many kinds of nanocarriers are demonstrat
Triple-negative breast cancer (TNBC) is an aggressive histological subtype with more limited therapeutic strategies and poorer prognoses in clinical trials,conventional treatments like hormone therapy
The spontaneous assembly ofmicroscale compartments is a central question for the origin of life.The compartments synthesized by chemical process have similar structure and functions as the cells,which
Polycations are widely used as chemical vectors to deliver nucleic acids.However,their clinical applications are limited owing to relatively low transfection efficacy,low stability in serum,and high c
Peripheral nerve injury has seriously affected peoples health and life.Nerve growth factor (NGF)is essential for neurons to promote their development,differentiation,growth,regeneration and other func
Cytomimetic vesicles not only provide simplified models for investigation of the cell behaviors but also show a variety of complex nanoparticle architectures inspired by cell structures or behaviors,w
Synthetic nucleic acid vectors have exhibited a great potential in cancer therapy compared with viral vectors[1].To achieve therapeutic effect,synthetic vectors must accomplish a series of tasks,inclu
Poly(ethylene glycol)-poly(lactic acid-co-glycolic acid) (PEG-PLGA)nanoparticles have been widely explored for drug controlled release owing to the "smart" solid-liquid phase transition.