【摘 要】
：
Objective To evaluate the clinical effects of nicardipine for inducing controlled hypotension in patients undergoing orthognathic surgery.Methods Two reviewers evaluated the quality of the included tr
【机 构】
：
Department of nesthesiology,Peking University School of Stomatology,Beijing 100081,China
【出 处】
：
第九次亚洲口腔麻醉学术会议暨2016全国口腔麻醉学术年会
论文部分内容阅读
Objective To evaluate the clinical effects of nicardipine for inducing controlled hypotension in patients undergoing orthognathic surgery.Methods Two reviewers evaluated the quality of the included trails and extracted the data from the RCTs indentified from English and Chinese literatures databases.The data were statistical analyzed using the RevMan 5.3.3 software.Results Finally 5 RCTs were included which involved 248 patients.The results from Meta-analysis and descriptive analysis indicated that blood loss of nicardipine group showed that there were more blood loss in the nicardipine group than those in the reifentanil group [WMD = 43.85,95%CI(20.52,67.18)].There was no significant difference in blood loss between the nicardipine group and the dexmedetomidine group and the nitroglycerin group.Meanwhile There was no significant difference in transfusion between the nicardipine group and the controlled group.Nicardipine was found to increase the heart rate during controlled hypotension and to cause QT prolongation(P < 0.001).Nicardipine has no adverse effects on cerebral oxygen saturation and neurophysiological function.Compared with the remifentanil group,the urinary N-acetyl-1-b-D-glucosaminidase was significant lower in the nicardipine group(P < 0.05).Conclusion Nicaridpine is effective to induce hypotension during orthognathic surgery,with potential renal protective effect.However,it is not better than the remifentanil on reducing the blood loss.Moreover nicardipine could increase the heart rate and prolong the QT interval during the controlled hypotension.High quality RCTs are needed.
其他文献
Aims: Bone injury has been occured in various clinical situations such trauma and surgeries.During surgery,excessive reactive oxygen species(ROS)decreases the quality and quantity of osteoblasts and i
目的 探讨右美托咪定对创伤后应激障碍(PTSD)大鼠焦虑状态和认知功能的影响.方法 将雄性SD 大鼠随机分为五组：对照组(C 组)、PTSD 模型组(P 组)和右美托咪定10ug/kg组(D1 组)、20ug/kg 组(D2 组)和40ug/kg 组(D3 组),通过条件性恐惧实验测定大鼠的恐惧记忆,旷场实验测定大鼠的自主活动能力和焦虑状态,高架十字迷宫测定大鼠的焦虑状态和水迷宫实验测定大鼠的空间
This topic will contain a review of quality indicators for practice.Included will be the national driving force for the indicators,the metrics,and how they are used for quality healthcare.
阐释全麻药物诱导意识消失的神经生物学机制,就必须从神经活动的结构基础入手。近年来,“神经环路”理论的引入与不断完善使得我们对“神经功能活动”的本质认识取得突破性的进展,神经环路被认为是脑功能重要的物质基础与平台。神经环路的解析,特别是环路不同维度或水平的动态变化及其所导致的神经行为或活动改变的阐明,对于解决如“How do general anesthetics work？”这样的神经科学难题具有
Background The incidence of Early Childhood Caries shows a significant increasing trend.Often,children younger than six years need additional help to finish the dental treatment.Therefore,the general
目的 分析我院51例口腔颌面外科术后带经鼻气管插管患者入麻醉复苏室后的镇痛镇静治疗中,氢吗啡酮1-2mg肌注增加患者气管导管耐受度.方法 选择2016年1月1日至2016年6月30日我院收治的51例全麻术后保留经鼻气管插管患者,所有患者均术后清醒送至麻醉复苏室,均使用PCIA术后镇痛治疗.将在复苏期间使用盐酸氢吗啡酮注射液1-2mg肌注复合镇静镇痛的15例患者分为A组,不使用该药物的36例患者分为
背景 早期儿童龋齿的发生率呈现出明显的上升趋势.通常来说,年龄小于6岁的儿童需要额外的措施才能完成口腔治疗.因此,全身麻醉可以为儿童口腔治疗提供一个良好的治疗环境.目的 通过使用P-CPQ 及FIS 问卷调查来评估全麻下口腔治疗对位于中国西南地区重庆的儿童口腔健康的影响.方法 我们收集了从2013年至2014年期间在重庆医科大学附属口腔医院接受全麻下口腔治疗儿童的就诊记录以及当时患儿家长在治疗前及
目的 分析1124例儿童在牙科治疗中通过喉罩全凭吸入麻醉下围手术期气道并发症的结果,并探讨牙科治疗下儿童麻醉的特点.方法 1124例患儿均使用七氟烷全凭吸入麻醉并使用喉罩进行气道管理.根据患儿的年龄特征,＜7岁的儿童进入A组,≥7岁的儿童进入B组.记录各组牙科治疗时围手术期的麻醉并发症.结果 通过两组儿童数据分析显示在插管期,B组出现3例(3.5％)肢体移动的患儿；麻醉维持期,喉罩移位的发病率在两
1.脓毒症定义：脓毒症是由针对感染的失控宿主反应导致的威胁生命的器官功能障碍.通俗地说，宿主针对病原微生物产生反应，伤害了自身组织器官，并产生致命性状况，称为脓毒症.2.脓毒症诊断标准：1)脓毒症：感染之后SOFA 总分急性变化≧2 分可确定为器官功能障碍.未知已有器官功能障碍的患者可假定其基线SOFA 评分为零.