【摘 要】
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Objective To investigate the distribution of A986S and R990Gpolymorphisms of CASR gene in Chinese population, and their relationship with the risk and clinical phenotypes of primary hyperparathyroidis
【机 构】
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Key Laboratory of Endocrinology of Ministry of Health Department of Endocrinology, Peking Union Medi
【出 处】
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中华医学会第七次全国骨质疏松和骨矿盐疾病学术会议
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Objective To investigate the distribution of A986S and R990Gpolymorphisms of CASR gene in Chinese population, and their relationship with the risk and clinical phenotypes of primary hyperparathyroidism (PHPT) in Chinese population.Patients and methods 164 consecutive Chinese Han PHPT patients (M/F: 51/113) and 230 healthy controls (M/F: 50/180) were enrolled.The clinical parameters in PHPT patients including biochemical markers, bone mineral density (BMD), kidney stone occurrence and pathological results were analyzed.Genotyping in both patients and controls was performed according to the standard procedures.
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