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肝纤维化(hepaticfibrosis)是指肝脏纤维组织过度沉积,是纤维增生(细胞外基质合成增加)和纤维分解(细胞外基质降解)不平衡的结果。肝纤维化是多种病因导致肝硬化的病理基础,故对慢性肝病的治疗除病因治疗外,应强调对肝纤维化的治疗,以减缓、阻止乃至逆转其病理?
Hepatic fibrosis refers to the excessive deposition of fibrous tissue in the liver as a result of an imbalance between fibrogenesis (increased extracellular matrix synthesis) and fibrolysis (extracellular matrix degradation). Liver fibrosis is the pathological basis of a variety of causes leading to cirrhosis, so the treatment of chronic liver disease in addition to the cause of treatment, should emphasize the treatment of liver fibrosis, to slow, prevent and even reverse its pathology?