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新生血管生成是肿瘤生长、入侵和转移的关键环节。软骨是一种无血管组织，对肿瘤的侵噬具有一定的抵抗性。经研究发现，牛和鲨鱼等动物的软骨中含有多种抗肿瘤活性成分，如血管生成抑制因子、抗肿瘤因子和抗入侵因子等。本文综述了近年软骨抗肿瘤活性物质研究的进展。
Neovascularization is a key link in tumor growth, invasion, and metastasis. Cartilage is an avascular tissue that is resistant to the invasion of tumors. The study found that cartilage in cattle and sharks contains a variety of anti-tumor active ingredients, such as angiogenesis inhibitors, anti-tumor factors and anti-invasion factors. This article reviews recent advances in cartilage antitumor active substances research.