Objective We conduct aerobic endurance training guidelines based on healthy information in order to improve training efficiency, reduce sport injuries, control the cardiovascular risk of movement, and promote the scientificity and systematicness of fitness training.Methods We selected 109 male students randomly to observe for 3 months.Firstly they went with cardiovascular risk assessment, heart, lung function, bone strength and aerobic endurance test to collect healthy information.According to aerobic endurance level before training, we divided the subjects into aerobic endurance worst group (the minimum 30% of the VO2max), poor group (the middle 30% of the VO2max) and the normal group (the maximum 40% of the VO2max).Then we gave intervention to guide training in the first two groups and the normal group was guided training in accordance with the traditional scheme.We evaluated the scientificity and efficiency of intervention guidelines through cardiopulmonary function monitoring.Results All the participants improved greatly after training (P<0.05).The intervention effect on the students of aerobic endurance worst group and poor group was good, and the improvement was 1 to 3 times more than that of the normal group.The difference of the index in the three cardiovascular function and pulmonary function tests changed significantly (P<0.05).And fracture incidence was lower than the normal group.Conclusions The aerobic endurance training guidance scheme based on healthy information can significantly improve the students aerobic stamina level, with cardiovascular and pulmonary ventilation function improved, and can reduce sports injury.We suggest cardiovascular function and pulmonary function tests in the training in order to indirectly assess the improvement of cardiopulmonary endurance.