丙型肝炎病毒慢性感染和自发恢复病人T细胞反应的差异

来源 :第十一届全国病毒学学术研讨会暨第六届武汉现代病毒学国际研讨会 | 被引量 : 0次 | 上传用户：qq20881010

【摘要】

：

丙型肝炎病毒(HCV)在全球总共造成约3％的人慢性感染,但其治疗方案仍然很局限.目前,没有一种预防性或治疗性的疫苗可以控制HCV的传播.先前的研究发现,HCV特异性的T细胞反应对于病毒的清除至关重要.本项目中,我们利用HCV-1b亚型的共有序列,设计了一组能够覆盖HCV全长基因组的交叉重叠的多肽序列,并以此来研究不同类型病人HCV特异性T细胞反应.

【作者】

：

张超华瑞涂正坤张永宏郝沛钟劲陈新月牛俊奇金侠

【机构】

：

病毒疾病与疫苗转化研究组,上海巴斯德研究所,中国科学院,上海市吉林大学白求恩第一医院,吉林大学,

【出处】

：

第十一届全国病毒学学术研讨会暨第六届武汉现代病毒学国际研讨会

【发表日期】

：

2015年6期

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丙型肝炎病毒慢性感染和自发恢复病人T细胞反应的差异

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