In humans,fat digestion in small intestine is mainly due to the hydrolysis of lipids by pancreatic lipase.The physicochemical properties of the interracial layer surrounding fat droplets could play an important role in determining the extent of enzyme binding to the emulsion surface and therefore the extent of lipolysis.Our previous study confirmed that various polyglycerol esters of fatty acid (PGEs) surrounding emulsified lipids affected the stability of emulsions and the encapsulated lipophilic compounds during gastric digestion.The objective of this work was to investigate the influence of PGEs on in vitro digestion of emulsified oil by pancreatic lipase.