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Alvin Wong,Krista Hardy,Alex Kitajewski,Carrie J.Shawber,Jan Kitajewski,June K.Wu Purpose:Since 2008,propranolol has been accepted as a mainstay of medical therapy for complicated infantile hemangiomas (IH).However,its mechanism of action is not well understood.We hypothesize that propranolol accelerates hemangioma involution by favoring adipegenesis of HemSCs.