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Organometallic Ru(Ⅱ)/Os(Ⅱ) arene complexes of the type [(η6-arene)Ru(en)Cl]+,[1] where the arene= e.g.p-cymene,biphenyl(bip) or tetrahydroanthracene(tha) and en = ethylenediamine,are toxic to cancer cells,including cisplatin-resistant cell lines.