microRNA expression profiles derived from microvesicles and their functional roles in liver cirrhosi

来源 :中华医学会第十六次全国病毒性肝炎及肝病学术会议 | 被引量 : 0次 | 上传用户:usuke
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Background and ains Microvesicles (MVs) are membrane vesicles that are released from multiple cells.MVs contain proteins, lipids and nucleic acids of the original cells.The microRNAs (miRNAs) released from MVs combined with different target cells.The changes in the concentration of MVs miRNAs have been reported to concern with certain diseases, but little information is available for liver cirrhosis (LC).LC is one of the most important risk factors of hepatic cell cancer (HCC).
其他文献
Background Patients of chronic hepatitis B with acute exacerbation were usually followed by a spontaneous decline of HBV DNA.The subsequential antiviral therapy are controversial.In this study, we eva
会议
Background Standard therapy for CHC still faces many unmet medical needs.T.C.M.exhibit liver function protection, anti-fibrosis, immune function modulation and some extent anti-viral function in CHC t
会议
Introduction Hepatocellular carcinoma (HCC) is the third most common cause of death worldwide.The risk of developing HCC in patients suffering from cirrhosis is increased in the setting of chronic HCV
会议
Background Depression, a common side effect of interferon therapy in patients with chronic hepatitis C, is closely associated with antiviral dosage reduction, discontinuation and failure of treatment.
会议
Aim uncover the possible immune response to HBV naked core particle in hydrodynamic injection mice model.Methods Plasmids expressing wild type of HBV core protein (HBcWT), or HBcK96R mutation which ab
会议
Hepatitis B virus (HBV) polymerase (pol) gene has been demonstrated to play an important role in the progression of liver disease and in fulminant hepatitis.Previous studies from our laboratory have s
会议
原发性肝癌恶性程度高,起病隐匿,病情进展快,容易复发转移;而且我国肝癌多发生在肝炎、肝硬化基础之上,不仅造成机体的损伤,还降低肝脏的储备功能,严重影响肿瘤的治疗和预后.肝癌的治疗不仅需关注消除肿瘤本身,而且必须同时注重保护患者肝功能、减少肝功能损害.肝癌规范治疗的最主要评价标准是患者生存获益.
会议
Background Clinical use of bioartificial liver (BAL) strongly relies on the development of human liver cell lines.The aim of this study was to establish and assess the potential usage of the HepG2 cel
会议
Background & Aims The woodchuck model is an informative model for studies on hepadnaviral infection.In this study, woodchuck hepatitis virus (WHV) transgenic (Tg) mouse models based on C57BL/6 mice we
会议
We have previously shown that polyinosinic-polycytidylic acid (poly (I ∶ C)) activates murine hepatic cells to produce interferon (IFN) and suppresses HBV replication in vitro.Therefore, we addressed
会议