Asymmetric Alkynylation of Trifluoropyruvates with Terminal Alkynes Catalyzed by Chiral NCN Pincer R

来源 :第十八届全国金属有机化学学术讨论会 | 被引量 : 0次 | 上传用户:sunzhaojian
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The synthesis of optically active a-trifluoromethyl-substituted secondary and tertiary alcohols has received much attention due to their unique properties with unusual biological activities as drugs and its candidates [1].
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单中心均相烯烃聚合体系中的活性中心为离子对结构[Cp2MR]+[Aluminate]-1,中心金属离子被具有Lewis碱性的助催化剂包围,形成类似离子氛的笼状结构.聚合单体依靠分子扩散穿越由助催化剂组成的壳层到达聚合中心,进行聚合反应后聚合物分子再次依靠扩散逸出聚合笼.
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