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Enantioseparation is a significant subject in science and technology.Cyclodextrins (CDs) are cyclic oligosaccharides consisting of six or more α-(l,4)-linked D-glucopyranose units.The β-cyclodextrin molecule has secondary 2-and 3-hydroxyl groups lining the mouth of the cavity and primary 6-hydroxyl groups at the rear of the molecule.The cavity permits inclusion of hydrophobic portions of the solute molecules.Interaction of any polar regions of a solute molecule with the surface hydroxyls combined with the hydrophobic interactions in the cavity provides the 3-point interaction required for chiral recognition [1-4].